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Verification and Validation Technician

ANGLE plc

Verification and Validation Technician

Salary Not Specified

ANGLE plc, Guildford

  • Full time
  • Permanent
  • Onsite working

Posted 2 weeks ago, 18 May | Get your application in now before you miss out!

Closing date: Closing date not specified

job Ref: fbf73f6029c745c6b337cdfc9b4e25cf

Full Job Description

  • Responsible for accuracy, quality, integrity, and regulatory compliance of all work undertaken.

  • Hands-on bench work, primarily in the area of verifying and validating RUO/IVD instruments, assays and consumables in the ANGLE product range.

  • Support to provide assay performance data for ANGLE Clinical Laboratory certifications with CLIA, UKAS and other regulatory bodies as necessary.

  • Generating appropriate verification and validation documentation (V&V) through the undertaking of pre-defined studies and tasks; characterising product performance using various protein and nucleotide-based assays. Furthermore, supporting project transition through stages 3 and 5 of ANGLEs NPD process, developed by R&D team.

  • Support Computer System Validation (CSV) projects.

  • Support the development of verification and validation (V&V) documentation prior to V&V task delivery.

  • Provide additional ad-hoc scientific and technical support to manufacturing processes, quality processes, R&D programmes and projects.

  • Independently keep a current knowledge base in relevant areas of scientific and technical progress.

  • Contribute to managing the day-to-day running of assigned V&V activities within the Quality Management System (ISO13485:2016).

  • Undertake additional ad-hoc tasks as required.

    B.Sc. or equivalent in Life Science/Biomedical Science or Biomedical engineering. Alternatively, proven track record of laboratory experience gained in verification and validation for the in vitro diagnostics industry.

  • Understanding of programming computer software.

  • Organisational skills and the ability to follow agreed procedures is essential.

  • Managing and delivering production to agreed timetables and according to defined instructions.

  • Strong team player with excellent communication skills, work ethic and attention to detail.

  • Good report writing skills, with the ability to communicate results to technical and non-technical staff.

  • An eye for detail and commitment to high-quality data.

  • A flexible, can-do approach to the requirements of the job., Capable of learning, and understanding laboratory techniques and carrying out regular laboratory work.

    ANGLE is a world-leading liquid biopsy company commercialising a patent-protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.


    • ANGLE's Parsortix® system is FDA-cleared for its intended use in metastatic breast cancer and is currently the first and only FDA-cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. CTCs are cancer cells that have detached from the primary tumour and entered the blood circulation, and they play a critical role in initiating metastasis. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patients tumour, advancing cancer research and potentially personalized medicine. This technology has the potential to deliver profound improvements in clinical and health economic outcomes.

    ANGLE has established a CTC harvest and analysis service from our UK-based Clinical Laboratory based in Guildford for customers worldwide. In alignment with company priorities, we plan to rapidly expand our services to include molecular profiling of CTCs and ctDNA using digital PCR and NGS to add to our image-based assays.

    Join our Team:

    This is an exciting time at ANGLE and our team in Guildford are looking for a Verification and Validation Technician to contribute to ANGLEs NPD processes by verifying and validating products (RUO/IVD instruments, assays and consumables) developed by the R&D team and the Product Development team.

    The job is laboratory-based working in a multi-disciplinary team. Goals and routes are agreed weekly with the supervisor, but an ability to work independently is expected.

    At ANGLE, we foster a dynamic, entrepreneurial approach to translating leading edge translational research into clinical diagnostics. We promote a culture of collaboration and shared excellence while encouraging an open and honest exchange of ideas.

    We are always in search of potential employees who share our vision and want to make a difference today. In your submission, please describe your background and what you can bring to our team along with attaching your resume.,
  • Due to the nature of the role, our requirement is for this position to be office/lab-based at our Guildford site.


    • As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.